CENBIMO S.L

INTRODUCTION

Neurotensin is a 12 amino acid long peptide that is extensively found in all catecholamine producing neurons in the brain.

Its main physiological effect is to increase vascular permeability producing hypotension and cyanosis.

Some disperse neuroendocrine system cells also produce Neurotensin, principally those found in the small intestine and lung.

To date there have been described a small number of patients with neuroendocrine tumors that produced Neurotensin whose clinical presentation was very similar to that of VIPoma patients.

Some patients with pancreatic VIPomas also produce Neurotensin.

Histosonda Neurotensin consists of a single stranded DNA fragment that is 257 nucleotides long.

INTENDED USE

For use in In Vitro Diagnosis.

Histosonda Neurotensin is useful for the diagnosis of tumors producing this peptide.

WARNINGS AND PRECAUTIONS

Histosonda Neurotensin has been designed for professional use in In Vitro Diagnosis and must be manipulated by qualified and accordingly trained personnel. In order to obtain the best results, the instructions contained in the manual must be followed. Any change to the indicated temperatures, times or any other step of the process can lead to poor results.

KIT COMPONENTS

The kit includes 20 single test tubes of lyophilized

Histosonda Neurotensin.

Histosonda Neurotensin consists of a single stranded DNA fragment with a length of 257 nucleotides targeted against Neurotensin mRNA.