CENBIMO S.L

INTRODUCTION

Under normal conditions cells producing Pancreatic Peptide are scarce and are normally found in the peripheral zone of the Islets of Langerhans and also adjacent to the epithelium of the small ducts of the pancreas.

Pancreatic non functional neuroendocrine tumors are caused either by the fact that the protein being produced by the tumor is secreted in small quantities or that the protein or peptide produced is functionally inert.

One of the most frequent pancreatic non functional tumors is PPoma.

Many tumors producing Pancreatic Peptide are found in the pancreas but gangliocytic paragangliomas have also been described in the duodenum and some rectal neuroendocrine tumors also produce this peptide.

HISTOSONDA PP consists of a single stranded DNA fragment with a length of 238 nucleotides.

INTENDED USE

For use in In Vitro Diagnosis.

Histosonda Pancreatic Peptide is useful for the study of pancreatic and extrapancreatic neuroendocrine tumors and their metastases.

WARNINGS AND PRECAUTIONS

Histosonda Pancreatic Peptide has been designed for professional use in In Vitro Diagnosis and must be manipulated by qualified and accordingly trained personnel. In order to obtain the best results, the instructions contained in the manual must be followed. Any change to the indicated temperatures, times or any other step of the process can lead to poor results.

KIT COMPONENTS

The kit includes 20 single test tubes of lyophilized

Histosonda Pancreatic Peptide.

Histosonda Pancreatic Peptide consists of a single stranded DNA fragment with a length of 238 nucleotides.